Hair Loss Treatments: What Works and What Research Shows

Hair treatment methods

No single method suits everyone. Here we explain what each method does, how well it has been studied, and who it suits, so you can understand your options before your consultation. All treatments at the clinic are performed by Dr. Dana Buchbut herself, physician (M.D.).

The articles in this section were written and medically reviewed by Dr. Dana Buchbut, physician (M.D.), license no. 115672, member of the Israel Medical Association

In brief

Three treatment groups: medications (minoxidil, finasteride and dutasteride), regenerative scalp treatments (PRP, iPRF, CGF, MCT, stem cells - Regenera Activa, nanofat, mesotherapy and exosomes), and hair transplant using the FUE and DHI techniques.
Diagnosis first: the choice is made after a trichoscopic diagnosis, according to the type and stage of hair loss, not according to the name of the treatment.
Usually combined: a medication that slows progression, an in-clinic treatment that strengthens active follicles, and repeat measurement at the same points on the scalp.
Earlier is better: regenerative treatments strengthen follicles that are still active; a transplant is considered when balding is advanced and there is enough donor hair.

Hair treatment methods at a glance

Method	Made from	How it is given	Usual number of treatments
Minoxidil and finasteride	Medications	Topical application or tablet	Continuous daily use
PRP for hair	Your own blood, concentrated in platelets	Injection into the scalp	Three, one month apart, then maintenance
iPRF and CGF	Your own blood, without anticoagulant	Injection into the scalp	A series of several treatments about a month apart
Light-activated PRP (MCT)	PRP that undergoes activation by light and temperature	Injection into the scalp	Like PRP: a series, then maintenance
Stem cells - Regenera Activa	Tiny samples from the back of your scalp	Injection of a suspension into the thinning area	One treatment in most studies
Nanofat for hair	A small amount of your own fat, emulsified and filtered	Injection with a fine needle	One treatment or a few
Hair transplant (FUE and DHI)	Follicles from the back of the head	Transfer to the thinning area	A surgical procedure, alongside medication to preserve existing hair

The full comparison, including what the studies found: Comparison of regenerative treatments.

Blood concentrates

PRP and other concentrates from the patient's blood.

iPRF and CGF

iPRF and CGF are platelet and fibrin concentrates from your own blood, close relatives of PRP. How they differ, how they support the follicle, what a randomized trial comparing all three found, and who they suit.

PRP

PRP (platelet-rich plasma) is prepared from your own blood in a centrifuge and delivers growth factors to the tissue. How it is prepared, how it works, what the studies found, light activation, and who it suits.

PRP for hair

PRP for hair: a short blood draw, separation in a centrifuge and injection into the scalp. How it strengthens the follicles, what 43 controlled trials found, how many treatments you need and when you see a change.

How many PRP treatments for hair

How many PRP treatments for hair you need: a series of three treatments, when you see a change, how the response is assessed with trichoscopy, and why maintenance treatments continue. Medical information with sources.

PRP for hair in Tel Aviv

PRP for hair in Tel Aviv with Dr. Dana Buchbut: trichoscopic diagnosis, tailoring to the type of hair loss, a series of treatments, combination with minoxidil and finasteride, and what you can realistically expect from the treatment.

PRP for scars

PRP for scars: how growth factors from your own blood support collagen building, what meta-analyses show about combining it with microneedling and subcision, and who it suits.

PRP in Tel Aviv

PRP treatment in Tel Aviv for hair and face: how the treatment is performed, what the studies show, who it suits and who it does not, with no promises. Clinic at 11 HaBarzel St., Tel Aviv; book via WhatsApp or by phone.

The complete guide to PRP treatment

A step-by-step guide to PRP (plasma) treatment: consultation and diagnosis, tests, preparation, treatment day, follow-up, when to continue and when to stop, and choosing a treatment by goal: hair, face or scars.

PRP questions and answers

47 questions and answers about PRP treatment: what it is, whether it works, whether it hurts, whether it is safe, how many treatments you need and when you see results, for hair, face and scars. With research sources, no promises. Tel Aviv.

PRP or MCT: what is the difference

PRP or MCT (PRP activated by light and temperature): how each is prepared, how they differ, what is known from studies and what is not yet known, who each one suits, and what to ask before agreeing to treatment.

Stem cells - Regenera Activa

Stem cells - Regenera Activa: tiny samples from the back of the scalp are turned into a suspension rich in progenitor cells and growth factors, which is injected into the thinning area in a single visit. How it works and what the studies found.

Scalp Botox

Scalp Botox (botulinum injection) for hair loss, sweating and an oily scalp: how relaxing the scalp muscles improves blood flow to the follicles, what the studies found, and how it differs from "hair Botox".

Exosomes for hair

Exosomes and growth factors for hair: tiny vesicles that carry growth-promoting signals to the follicle. How it works, what the studies found on hair density, how they are delivered into the scalp, and what is important to know.

Mesotherapy

Mesotherapy for hair: small injections into the scalp of vitamins or medications such as dutasteride, delivering the active ingredient directly to the follicle. How it works, what the studies found, and who it suits.

Scalp phototherapy

Red-light helmet, cap or comb for hair: how light gives the follicle energy, what controlled trials in men and women found, how to combine it with minoxidil and PRP, and how to choose a home device.

Hair transplant

Hair transplant using the FUE and DHI techniques: the difference, who is a candidate, what transplant day is like, recovery, and what happens after 3, 6 and 12 months. Medical information with sources.

Transplant abroad

Considering a hair transplant in Turkey? A checklist of questions before you fly, how to prepare your scalp at home in Israel, and what to do after you return so the result looks good for years.

After a hair transplant

What to do after a hair transplant: washing, sleeping, exercise and sun in the first weeks, and why long-term medication and PRP are needed so your original hair does not keep falling out.

DHI hair transplant

DHI hair transplant: direct implantation with a dedicated pen, how it differs from FUE and how it does not, who it suits, recovery, what to expect, and what the research says. Medical information with sources.

FUE hair transplant

FUE hair transplant: how individual follicles are extracted, who it suits, what recovery looks like, what to expect over the first year, and what the risks are. Medical information with sources.

Temple and hairline transplant

Hair transplant at the temples: how a natural hairline is planned, the right height and shape, why caution is taken with a hairline that is too low at a young age, and how a female hairline differs. Medical information with sources.

Hair transplant for men

Hair transplant for men: how to know whether it is the right time, why age and stability matter, how much donor hair there is, and why existing hair continues to be treated even after the transplant. Medical information with sources.

No-shave hair transplant

No-shave hair transplant: how follicles are extracted between the hairs, the difference between partial shaving, trimming and long hair, who it suits, the limitations, and what recovery looks like.

Scabs and redness after a transplant

Scabs, redness, itching and swelling after a hair transplant: how long each lasts, how to care for them gently, what not to do, and when to contact the clinic. Medical information with sources.

Shock loss

Shock loss after a hair transplant: when it appears, when the hair returns, who is at risk, how to reduce it with medication and PRP, and when the shedding is something else.

Synthetic hair implants

Synthetic hair implants (artificial fibers): what they are, how they differ from a natural hair transplant, the complications that have been documented, their regulatory status in the US, and the natural options.

Hair transplant over time

Long-term hair transplant results: what happens in the first weeks, why the transplanted hair falls out, when growth begins, when you see the result, and whether a hair transplant lasts a lifetime.

Hair transplant for women

Hair transplant for women: how suitability is assessed, which thinning patterns it suits, how long hair is preserved, what recovery is like, and the options when thinning is diffuse. Medical information with sources.

Tailored home treatment

Minoxidil, finasteride, shampoos and supplements: what is evidence-based and what is not, how long it takes to see a change, side effects, and why a home plan should be built after diagnosis.

Biotin for hair

Biotin (vitamin B7) and hair: what biotin is, when a supplement helps, who is at risk of deficiency, biotin in mesotherapy preparations, and what is important to know before blood tests.

CGF for hair

CGF for hair is a growth factor concentrate from your own blood, rich in fibrin and platelets. How it supports the follicles, what trials found compared with PRP and alongside hair transplant, and what the treatment looks like.

CGF in Tel Aviv

CGF in Tel Aviv: a growth factor concentrate from your own blood. What it is, how it differs from PRP, what is known and what has not yet been proven for hair and skin, who it suits, and how the treatment is performed at the clinic at 11 HaBarzel St.

What exosomes are derived from

Exosomes for hair: what they are, exactly how they stimulate the hair follicle, and what they are derived from: the patient's own body, human cells, or plants such as rose. Including registration status in Israel.

Finasteride

The men's guide to finasteride (Propecia): how it stops balding, what five-year studies showed, what is known about side effects and mood, topical finasteride, and what happens when you stop.

Finasteride side effects

Side effects of finasteride for hair loss: how common the sexual side effects are, what about mood, whether they go away, how to tell the nocebo effect from the drug, and when to see a doctor.

What growth factors are derived from

Growth factors for hair: VEGF, IGF-1, KGF, PDGF, EGF and HGF: what each does for the follicle, and where they come from: your own blood (PRP, iPRF, CGF), human cells, peptides or synthetic serum.

Anti-hair-loss shampoo

Does an anti-hair-loss shampoo stop hair loss? What the studies say about ketoconazole, caffeine and rosemary, shampoo for women and shampoo for men, and when shampoo does help.

iPRF for hair

iPRF for hair: a concentrate from your own blood with no anticoagulant and no additives, which forms a fibrin network and releases growth factors over several days. What the studies found, what the treatment looks like, and who it suits.

iPRF in Tel Aviv

iPRF in Tel Aviv with Dr. Dana Buchbut: a concentrate from your own blood without anticoagulant, for hair and skin. What is known and what is not yet known from research, who it suits, and how the treatment is performed. To book a consultation.

Ketoconazole shampoo

Ketoconazole shampoo for hair loss: what studies showed in hereditary hair loss, when it really helps, how to wash with it, side effects, and how to include it in a treatment plan.

AnteAGE for hair

What is in AnteAGE MD hair solution, how the conditioned medium and peptides support the follicle, how it is used with microneedling, who it suits, and side effects.

AQ Advanced Hair Complex

AQ Advanced Hair Complex is a growth factor serum from the conditioned medium of skin cells, given with microneedling and as a home topical. How it works, what is known from studies, and who it suits.

Azelaic acid

Does azelaic acid help with hair loss? A possible mechanism, the limited evidence for hair, its established uses in acne and rosacea, side effects, and what is known about scalp injection.

Cellbooster Hair

Cellbooster Hair combines hyaluronic acid, amino acids, vitamins and minerals to nourish the scalp. How it works, what the study found, who it suits, and how it is combined with other treatments.

Dr CYJ Hair Filler

What is in Dr CYJ Hair Filler for scalp injection, how biomimetic peptides and hyaluronic acid support the hair follicle, who it suits, and how it is given.

Injectable dutasteride

Dutasteride mesotherapy for hair loss: how blocking DHT directly in the scalp protects the follicle, what studies show on density and thickness, who it suits, and how it is combined with other treatments.

Growth factors for hair

Growth factor preparations for the scalp (conditioned medium): what they are, how they support the hair follicle, what the studies found, who they suit, and how they are combined with PRP, microneedling and medications.

Hair loss medications

The medications that stop hereditary hair loss: minoxidil, finasteride, dutasteride and azelaic acid, and how they are given: topically, as a pill, and by scalp injection. What the research shows, and who they suit.

Toskani HCPR

What is in Toskani HCPR, how peptides, vitamins and amino acids support the hair follicle, how it is given with microneedling, and who it suits.

HRLV

What is in the HRLV exosome preparation for the scalp, how exosomes, biotin and copper peptide support the follicle, what was reported in research, who it suits, and how it is combined with other treatments.

Hyaluronic acid and peptides

How cocktails of hyaluronic acid, peptides and amino acids support the hair follicle, what the studies show, who they suit, and how they are combined with other treatments.

Jalupro

Jalupro combines hyaluronic acid with four amino acids that nourish the tissue around the follicle. How it works, how it is combined with PRP and microneedling, and who it suits.

Injectable minoxidil

Minoxidil injected into the scalp (minoxidil mesotherapy): how it works, what trials and reviews found, how it differs from topical application, and what is important to know about safety before deciding.

Polynucleotides (PDRN, salmon DNA) for hair

Polynucleotides and PDRN injected into the scalp: how they support tissue repair and blood flow around the follicle, what was found in hair trials, combination with PRP, and who it suits.

PolyPhil

PolyPhil Hair is a polynucleotide preparation (PDRN, salmon DNA) that supports tissue repair and blood supply to the follicle. How it works, what the studies show, and how it is combined with other treatments.

Vitamin B6

Vitamin B6 for hair: how it supports the building of hair proteins, what studies found, who is at risk of deficiency, how it fits into scalp mesotherapy, and what the safe dose is.

Vitamins in mesotherapy

Vitamins in scalp mesotherapy: how vitamins and minerals support the follicle and the production of hair proteins, what studies found, who it suits, and how it is combined with other treatments.

Microneedling for hair

Microneedling and dermarollers for the scalp in hereditary hair loss: how the tiny punctures stimulate the follicle and improve minoxidil penetration, what the trials showed, and how to do it at home.

Minoxidil

Topical minoxidil for hair loss: how it works, liquid or foam, 2% or 5%, how long until you see a change, initial shedding, side effects, and what happens when you stop.

Minoxidil 2% or 5%

Minoxidil 2% or 5%? What trials in men and women showed, whether 5% is more effective, what about itching and facial hair growth, and how to choose a concentration and form, liquid or foam.

Foam or solution

Minoxidil foam or solution (liquid)? The difference between minoxidil 5% foam and liquid, why the solution itches more, what about absorption and styling, and when it is worth switching. With sources.

Stopping minoxidil

Stopping minoxidil? What happens to your hair and how quickly, whether minoxidil is for life, what the studies say, and how to make the right decision with a doctor. With sources.

Nanofat for hair

Nanofat for hair: a small amount of your own fat is turned into a fluid rich in cells and growth factors, which is injected into the scalp and improves the ground in which the follicle grows. What the studies found and who it suits.

Laughing gas

Laughing gas (nitrous oxide and oxygen) reduces pain and anxiety during scalp injections: you stay awake and relaxed, and the effect wears off within minutes. What it feels like, what the studies found, and who it suits.

Light-activated PRP (MCT)

MCT for hair loss: your PRP undergoes activation by light and temperature before injection, to release growth factors over time and autologous exosomes. How it works, how it differs from regular PRP, and what is known.

Comparison of regenerative treatments

A comparison of regenerative hair treatments: PRP, iPRF and CGF, light-activated PRP (MCT), stem cells - Regenera Activa, exosomes and nanofat. What they are made from, how many treatments, and what the research shows.

Restoration or transplant

Hair restoration (PRP, mesotherapy, medications) or hair transplant? How to decide according to the stage of balding, the donor area, age, the stability of the hair loss and the thinning pattern, and why the two are usually combined.

Scalp steroid injections

Steroid injection into the scalp for alopecia areata, lichen planopilaris, FFA and other inflammatory scalp diseases: the goal in each condition, what is known from research, and side effects.

Tricopat

Tricopat for hair loss: superficial micro-incisions, a growth factor serum, iontophoresis and red light in a single treatment. How it delivers substances to the follicle, what the studies found, and its registration status in Israel.